INTERVENTION IN GENE REGULATORY NETWORKS

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" INTERVENTION IN GENE REGULATORY NETWORKS "

Document Type	:	Latin Dissertation
Language of Document	:	English
Record Number	:	149363
Doc. No	:	ET21155
Main Entry	:	ASHISH CHOUDHARY
Title Proper	:	INTERVENTION IN GENE REGULATORY NETWORKS
Note	:	This document is digital این مدرک بصورت الکترونیکی می باشد
Abstract	:	In recent years Boolean Networks (BN) and Probabilistic Boolean Networks(PBN) have become popular paradigms for modeling gene regulation. A PBN is acollection of BNs in which the gene state vector transitions according to the rulesof one of the constituent BNs, and the network choice is governed by a selectiondistribution.Intervention in the context of PBNs was first proposed with an objective of avoid-ing undesirable states, such as those associated with a disease. The early methods ofintervention were ad hoc, using concepts like mean first passage time and alterationof rule based structure. Since then, the problem has been recognized and posed asone of optimal control of a M.
Subject	:	Electericl tess
	:	برق
electronic file name	:	TL44304.pdf
Title and statement of responsibility and	:	INTERVENTION IN GENE REGULATORY NETWORKS [Thesis]