A Hybrid Planar Patch-Clamp System for the Characterization of Ion Channels in Biological Cells

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" A Hybrid Planar Patch-Clamp System for the Characterization of Ion Channels in Biological Cells "

Document Type	:	Latin Dissertation
Language of Document	:	English
Record Number	:	148816
Doc. No	:	ET20608
Main Entry	:	Santosh K. Pandey
Title Proper	:	A Hybrid Planar Patch-Clamp System for the Characterization of Ion Channels in Biological Cells
Note	:	This document is digital این مدرک بصورت الکترونیکی می باشد
Abstract	:	Ion-channels are proteins embedded in cell membranes that regulate the flow of ionsacross the cellular boundary, thereby maintaining the cell's delicate chemical balance. More than40 of the known human diseases are directly or indirectly related to dysfunctions in ion-channels. At present, a method called patch-clamping is the gold standard for studying ion-channel activity; however, it suffers from a lack of high-throughput-screening (HTS) and highcost per data point. As the Human Genome Project unravels a wealth of genetic information andcombinatorial chemistry.
Subject	:	Electericl tess
	:	برق
electronic file name	:	TL43748.pdf
Title and statement of responsibility and	:	A Hybrid Planar Patch-Clamp System for the Characterization of Ion Channels in Biological Cells [Thesis]