FLEXIBLE MICROFLUIDIC SYSTEMS FOR CELLULAR ANALYSIS USING LOW COST FABRICATION TECHNOLOGIES

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" FLEXIBLE MICROFLUIDIC SYSTEMS FOR CELLULAR ANALYSIS USING LOW COST FABRICATION TECHNOLOGIES "

Document Type	:	Latin Dissertation
Language of Document	:	English
Record Number	:	150214
Doc. No	:	ET22006
Main Entry	:	Eileen Devra Moss
Title Proper	:	FLEXIBLE MICROFLUIDIC SYSTEMS FOR CELLULAR ANALYSIS USING LOW COST FABRICATION TECHNOLOGIES
Note	:	This document is digital این مدرک بصورت الکترونیکی می باشد
Abstract	:	This dissertation presents the design, fabrication, and testing of a microfluidic system tobe used for whole-cell analysis. The study of cellular function and structure is essential fordisease diagnosis and treatment. Microsystems developed to perform these bioanalyses addbenefits such as requiring smaller samples and reagents, testing multiple samples in parallel,and supporting point-of-care testing, all of which increases throughput and reduces cost-per-analysis. Traditional methods for designing a microsystem use standard materials andtechniques such as silicon, glass, photolithography, and wet and dry etching. This researchis focused on utilizing materials and techniques that require less infrastructure, allow fora faster design-to-prototype cycle, and can integrate electrical and fluidic functionality toaddress a variety of possible applications.The microfluidic system presented here is comprised of multiple layers of Kapton R, apolyimide available from DuPont. Kapton R provides a biocompatible substrate that isflexible while maintaining structural stability and can be used in high temperature andother harsh environments. Microchannels with widths of 400 m and thru-hole fluidic viasless than 5 m in diameter are laser ablated through the flexible polyimide sheets usingexcimer and CO2 lasers. Electrical traces and contact pads are defined on the substrate by..,..tested for theQ1 PC1 bus cardBoth these projects mere sofixare des elopment efforts tonards contributing to dlfferentaspects of Roboucs and lZ1echatronics projects m the Controls and Roboucs Group..
Subject	:	Electericl tess
	:	برق
electronic file name	:	TL45202.pdf
Title and statement of responsibility and	:	FLEXIBLE MICROFLUIDIC SYSTEMS FOR CELLULAR ANALYSIS USING LOW COST FABRICATION TECHNOLOGIES [Thesis]